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Item A | Modification |
A1 | Acetylation (N-Terminal) |
A2 | Fmoc(N-Terminal) |
A3 | Amidation (C-Terminal) |
A4 | Z (CBZ) (N-Terminal) |
A5 | Bz (N-Terminal) |
A7 | Br-Ac- {N terminus)} |
A8 | Formylation (N-Terminal) |
A9 | Fatty acid (N-Terminal) |
A10 | Myristic acid (N-Terminal) |
A11 | Palmytolyl (N-Terminal) |
A12 | Suc (N-Terminal) |
A13 | pNA (C-Terminal) |
A14 | AMC ( C-Terminal) |
A15 | CMK (C-Terminal) |
A16 | FMK (C-Terminal) |
A17 | Cysteamide ( C-Terminal) |
A18 | {HPP},3-(p-Hydroxyphenyl)propionic Acid (N-Terminal) |
A19 | {Mpa} (N-Terminal) |
A20 | {pGlu} (N-Terminal) |
A21 | DL-Lipoic acid (N-Terminal) |
A22 | {Maleoyl-b-Ala}, Maleimide (N-Terminal) |
Item B | Special amino acid |
B1 | {D-2-Me-Trp} |
B2 | {Ser(octanoic acid)} |
B3 | {Lys(Me)} |
B4 | {Lys(Me2)} |
B5 | {Lys(Me3)} |
B6 | {Lys(Dde)} |
B7 | {Lys(Alloc)} |
B8 | {D-Ile} |
B9 | {D-Orn} |
B10 | {D-Gln} |
B11 | {D-Cit} |
B12 | {Dab} |
B13 | {Dap} |
B14 | {D-Beta-Asp} |
B15 | {D-Gama-Glu} |
B16 | {D-Arg} |
B17 | {D-Cys} |
B18 | {D-Asp} |
B19 | {D-Asn} |
B20 | {D-Glu} |
B21 | {D-Ser} |
B22 | {D-His} |
B23 | {D-Tyr} |
B24 | {D-Thr} |
B25 | {D-Trp} |
B26 | {D-Lys} |
B27 | {Orn} |
B28 | {Abu} |
B29 | {Aib} |
B30 | {Nva} |
B31 | {Nle} |
B32 | {Cit} |
B33 | {Lys(Ac)} |
B34 | {Cys(Me)}, SMC |
B35 | {Cys(Cam)} |
B36 | {Cys(Acm)} |
B37 | {Cys(tBu)} |
B38 | {Hse} |
B39 | {Hcy} |
B40 | {D-Pen} |
B41 | {Cha} |
B42 | {D-Cha} |
B43 | {Chg} |
B44 | {D-Chg} |
B45 | {D-1-Nal} |
B46 | {L-1-Nal} |
B47 | {D-2-Nal} |
B48 | {L-2-Nal} |
B49 | {D-2-Pal} |
B50 | {L-2-Pal} |
B51 | {D-3-Pal} |
B52 | {L-3-Pal} |
B53 | {D-4-Pal} |
B54 | {L-4-Pal} |
B55 | {D-4-Cl-Phe} |
B56 | {L-4-Cl-Phe} |
B57 | {D-4-F-Phe} |
B58 | {L-4-F-Phe} |
B59 | {D-4-NO2-Phe} |
B60 | {L-4-NO2-Phe} |
B61 | {D-4-I-Phe} |
B62 | {L-4-I-Phe} |
B63 | {Beta-Asp} |
B64 | {Gama-Glu} |
B65 | {D-Ala} |
B66 | {D-Leu} |
B67 | {D-Met} |
B68 | {D-Pro} |
B69 | {D-Phe} |
B70 | {D-Val} |
B71 | {Hyp} |
B72 | {Phg} |
Item C | Spacer Linker |
C1 | {Mini-PEG} |
C2 | {Ava}, C5 |
C3 | {Ahx}, C6 |
C4 | {GABA}, C4 |
C5 | {Beta-Ala}, C3 |
C6 | {Gly}, C2 |
Item D | N-Methyl amino acid |
D1 | {N-Me-Ala} |
D2 | {N-Me-Phe} |
D3 | {N-Me-Leu} |
D4 | {N-Me-Ile} |
D5 | {N-Me-Val} |
D6 | {N-Me-Met} |
D7 | {N-Me-Nle} |
D8 | {N-Me-Nva} |
D9 | {N-Me-Gly}, Sar |
D10 | {N-Me-Ser} |
D11 | {N-Me-Tyr} |
D12 | {N-Me-Thr} |
D13 | {N-Me-Asp} |
D14 | {N-Me-Glu} |
Item E | Phosphorylation |
E1 | {pSer} |
E2 | {pTyr} |
E3 | {pThr} |
E4 | Di-sites in sequence |
E5 | Tri-sites in sequence |
Item F | Fluorescence/Dye Labeling |
F1 | Biotin (N-Terminal) |
F2 | Biotin-LC (N-Terminal) |
F3 | 3-Indolylacetic acid |
F4 | FITC (N-Terminal) |
F5 | FITC-LC (N-Terminal) |
F6 | 5-FAM (N-Terminal) |
F7 | 5-FAM-LC (N-Terminal) |
F8 | Dansyl (N-Terminal) |
F9 | Dansyl-LC (N-Terminal) |
F10 | MCA (N-Terminal) |
F11 | TMR (N-Terminal) |
F12 | Lys(Biotin) (middle) |
F13 | Lys(Biotin) (C temrinus) |
F14 | Lys(FITC) (middle) |
F15 | Lys(FITC) (C temrinus) |
F16 | Lys(5-FAM) (middle) |
F17 | Lys(5-FAM) (C temrinus) |
F18 | Lys(Dansyl) (middle) |
F19 | Lys(Dansyl) (C temrinus) |
F20 | Lys(TMR) (middle) |
F21 | Lys(TMR) (C temrinus) |
F22 | {Lys(Dnp)} (middle) |
F23 | EDBiotin (C terminus) |
F24 | EDDnp (C terminus) |
F25 | {Lys(Maleimide)}, (middle) |
Item G | Cyclic peptide |
G1 | Mono Disulfide bridge |
G2 | Double Disulfide bridge |
G3 | Triple Disulfide bridge |
G4 | Same Seq. Inter-Disulfide bridge |
G5 | Different Inter-Disulfide bridge |
G6 | Amide cyclic (end) |
G7 | Amide cyclic (Side chain) |
Item H | Quenched fluorescent peptide |
H1 | Abz/ Tyr (3-NO2) |
H2 | Abz |
H3 | Tyr (3-NO2) |
H4 | Glu(EDANS)-NH2 |
H5 | DABCYL |
H6 | DABCYL/Glu(EDANS)-NH2 |
Item I | MAPS and Carrier Complex |
I1 | Asymmetric 2 Branches (Pure) |
I2 | Asymmetric 4 Branches (Crude) |
I3 | Asym metric 8 Branches (Crude) |
I4 | Glu 2 Branches (Pure) |
I5 | n-mer Branch peptide on Lys side chain (Pure) |
I6 | KLH-Peptide |
I7 | BSA-Peptide |
Item J | C Terminus Modification |
Item Ja | C terminus ended amino acids: Ala, Gly, Met, Leu, Ile, Phe, Pro, Val |
Ja1 | -OMe (C-terminal) |
Ja2 | -OEt (C-terminal) |
Ja3 | -OBzl (C-terminal) |
Ja4 | -OtBu (C-terminal) |
Ja5 | -TBzl (C-terminal) |
Ja6 | -NHMe (C-terminal) |
Ja7 | -NHEt (C-terminal) |
Ja8 | -NHisopen (C-terminal) |
Item Jb | C terminus ended amino acids: Lys, Gln, Asn, Cys, His, Arg, Ser, Thr, Tyr, Trp, Asp, Glu |
Jb1 | -OMe (C-terminal) |
Jb2 | -OEt (C-terminal) |
Jb3 | -OBzl (C-terminal) |
Jb4 | -OtBu (C-terminal) |
Jb5 | -TBzl (C-terminal) |
Jb6 | -NHMe (C-terminal) |
Jb7 | -NHEt (C-terminal) |
Jb8 | -NHisopen (C-terminal) |
Item K | Aliquoting |
Item L | GMP Clean Room Process |
Item M | Amino Acid Analysis (AAA) |
Item N | N elemental Analysis |
Item O | Solubility test |
Item P | Microbial analysis |
Item Q | Water content (Karl Fischer) |
Item R | Acetate Content (HIPC) |
Item S | Maldi-Tof MS |
Item T | Endotoxin analysis |