XRCC4 purified MaxPab mouse polyclonal antibody (B01P)
产品名称： XRCC4 purified MaxPab mouse polyclonal antibody (B01P)
英文名称： XRCC4 purified MaxPab mouse polyclonal antibody (B01P)
产品编号： H00007518-B01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human XRCC4 protein.
- Immunogen:
- XRCC4 (NP_071801.1, 1 a.a. ~ 336 a.a) full-length human protein.
- Sequence:
- MERKISRIHLVSEPSITHFLQVSWEKTLESGFVITLTDGHSAWTGTVSESEISQEADDMAMEKGKYVGELRKALLSGAGPADVYTFNFSKESCYFFFEKNLKDVSFRLGSFNLEKVENPAEVIRELICYCLDTIAENQAKNEHLQKENERLLRDWNDVQGRFEKCVSAKEALETDLYKRFILVLNEKKTKIRSLHNKLLNAAQEREKDIKQEGETAICSEMTADRDPVYDESTDEESENQTDLSGLASAAVSKDDSIISSLDVTDIAPSRKRRQRMQRNLGTEPKMAPQENQLQEKENSRPDSSLPETSKKEHISAENMSLETLRNSSPEDLFDEI
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of XRCC4 expression in transfected 293T cell line (H00007518-T01) by XRCC4 MaxPab polyclonal antibody.
Lane 1: XRCC4 transfected lysate(36.96 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of purified MaxPab antibody to XRCC4 on formalin-fixed paraffin-embedded human adrenal gland. [antibody concentration 3 ug/ml]
- Protocol Download
- Immunofluorescence
enlarge this image- Immunofluorescence of purified MaxPab antibody to XRCC4 on HeLa cell. [antibody concentration 10 ug/ml]
- Protocol Download
- Entrez GeneID:
- 7518
- GeneBank Accession#:
- NM_022406.1
- Protein Accession#:
- NP_071801.1
- Gene Name:
- XRCC4
- Gene Alias:
- -
- Gene Description:
- X-ray repair complementing defective repair in Chinese hamster cells 4
- Omim ID:
- 194363
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq
- Other Designations:
- DNA repair protein XRCC4,X-ray repair cross complementing protein 4,X-ray repair, complementing defective, repair in Chinese hamster
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Ataxia telangiectasia
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Papillary
- Carcinoma, Squamous Cell
- Carcinoma, Transitional Cell
- Colorectal Neoplasms
- DNA Damage
- Endometriosis
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Genomic Instability
- Glioma
- Hematologic Diseases
- Hodgkin Disease
- Kidney Failure, Chronic