分子量：Calculated MW: 16kDa/23kDa
Observed MW: 25kDa

细胞定位：Mitochondrion membrane, Single-pass membrane protein

稀释方法：WB 1:500 - 1:2000
IHC 1:50 - 1:100

总结：The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.