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上海信裕生物科技有限公司
GRB2抗体

GRB2抗体

商家询价

产品名称： GRB2抗体

英文名称： GRB2Antibody

产品编号： XY10254-2

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 GRB2抗体

Applications
In-house applications ELISA, WB, IF     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
Prev1NextView more validation data
  • 10254-2-AP;HEK-293 cellHEK-293 cells were subjected to SDS PAGE followed by western blot with 10254-2-AP(GRB2 antibody) at dilution of 1:1000
  • 10254-2-AP;C2C12 cellsC2C12 cells (shcontrol and shRNA of GRB2) were subjected to SDS PAGE followed by western blot with 10254-2-AP(GRB2 antibody) at dilution of 1:1000. (Data provided by Angran Biotech (www.miRNAlab.com)).
  • 10254-2-AP;HEK-293 cellsImmunofluorescent analysis of HEK-293 cells using 10254-2-AP( GRB2 Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Positive WB detected in HEK-293 cells, A431 cells, C2C12 cells, rat brain tissue, rat spleen tissue
Positive IF detected in HEK-293 cells
Recommended dilution WB : 1:500-1:5000
IF : 1:10-1:100
GRB2抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen GRB2 fusion protein ag0395 Full name Growth factor receptor-bound protein 2
Calculated molecular
weight		 25 kDa Observed molecular 
weight		 25-28kd
GenBank accession 
number		 BC000631 Gene ID (NCBI) 2885
Gene symbol GRB2 Synonyms Adapter protein GRB2, ASH, EGFRBP GRB2, GRB2, Grb3 3, MST084, MSTP084, Protein Ash, SH2/SH3 adapter GRB2
BackgroundGRB2抗体

GRB2 (growth factor receptor-bound protein 2) binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. N-SH3 domain of Grb2 was involved in the protein vesicular localization including amyloid-β protein precursor (AβPP). Involvement of GRB2 in Ras-signaling pathway has been reported, recent finding show that GRB2 may also play a complex role in T and B-cell antigen receptor signaling.GRB2抗体

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