细胞周期蛋白依赖性激酶抑制剂2B抗体
产品名称: 细胞周期蛋白依赖性激酶抑制剂2B抗体
英文名称: CDKN2B/p15 INK4b
产品编号: bs-4269R
产品价格: null
产品产地: 北京
品牌商标: BIOSS
更新时间: 2024-06-07T08:51:26
使用范围: WB=1:100-500,ELISA=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,
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p15 INK4b / MTS 2 (Mitotic Inhibitor / Suppressor Protein) is a specific inhibitor of cdk 4 / cdk 6 and is periodically expressed during the cell cycle. Reportedly, p15 INK4b expression is induced approximately 30 fold in human keratinocytes by treatment with TGF beta, suggesting that p15 INK4b may act as an effector of TGF beta mediated cell cycle arrest. p15 INK4b is mapped to chromosome 9p21, a region of frequent loss in a wide variety of cancers.