GFRA2 polyclonal antibody
产品名称： GFRA2 polyclonal antibody
英文名称： GFRA2 polyclonal antibody
产品编号： PAB9888
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of GFRA2.
- Immunogen:
- A synthetic peptide corresponding to amino acids 377-391 of human GFRA2.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (1:1000-1:2000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Neurturin responsiveness requires a GPI-linked receptor and the Ret receptor tyrosine kinase.
Buj-Bello A, Adu J, Pinon LG, Horton A, Thompson J, Rosenthal A, Chinchetru M, Buchman VL, Davies AM.Nature. 1997 Jun 12;387(6634):721-4.
- 2.
- TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret.
Baloh RH, Tansey MG, Golden JP, Creedon DJ, Heuckeroth RO, Keck CL, Zimonjic DB, Popescu NC, Johnson EM Jr, Milbrandt J.Neuron. 1997 May;18(5):793-802.
- Entrez GeneID:
- 2675
- Gene Name:
- GFRA2
- Gene Alias:
- GDNFRB,NRTNR-ALPHA,NTNRA,RETL2,TRNR2
- Gene Description:
- GDNF family receptor alpha 2
- Omim ID:
- 601956
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- GFR-alpha 2,PI-linked cell-surface accessory protein,RET ligand 2,TGF-beta related neurotrophic factor receptor 2,TRN receptor, GPI-anchored,glial cell line derived neurotrophic factor receptor, beta,glial cell line-derived neurotrophic factor family rece