• 特异性This antibody detects endogenous levels of total MVD protein.
• 经测试应用IHC-Pmore details
• 种属反应性
  与反应: Human
  预测可用于: Mouse, Rat
• 免疫原

  Synthetic peptide corresponding to Human MVD (internal sequence).
  Database link: P53602

• 阳性对照
  • Human brain tissue.

性能

• 形式Liquid
• 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
• 存储溶液pH: 7.3
  Preservative: 0.05% Sodium azide
  Constituents: 49% PBS, 50% Glycerol
• 浓度100 µl 浓度为 1 mg/ml 
  
• 纯度Immunogen affinity purified
• 克隆多克隆
• 同种型IgG
• 研究领域
  • Cardiovascular
   
  • Lipids / Lipoproteins
   
  • Lipid Metabolism
  • Cholesterol Metabolism

  • Signal Transduction
   
  • Metabolism
   
  • Lipid metabolism

  • Cancer
   
  • Cancer Metabolism
   
  • Metabolic signaling pathway
  • Metabolism of lipids and lipoproteins

  • Metabolism
   
  • Pathways and Processes
   
  • Metabolic signaling pathways
  • Lipid and lipoprotein metabolism
   
  • Lipid metabolism

  • Metabolism
   
  • Pathways and Processes
   
  • Metabolic signaling pathways
  • Lipid and lipoprotein metabolism
   
  • Cholesterol Metabolism

应用

靶标

• 功能Performs the first committed step in the biosynthesis of isoprenes.
• 组织特异性Expressed in heart, skeletal muscle, lung, liver, brain, pancreas, kidney and placenta.
• 通路Steroid biosynthesis; cholesterol biosynthesis.
• 序列相似性Belongs to the diphosphomevalonate decarboxylase family.
• Information by UniProt
• 数据库链接
  • Entrez Gene: 4597 Human
  • Entrez Gene: 192156 Mouse
  • Entrez Gene: 81726 Rat
  • Omim: 603236 Human
  • SwissProt: P53602 Human
  • SwissProt: Q99JF5 Mouse
  • SwissProt: Q62967 Rat
  • Unigene: 252457 Human

  see all
• 别名
  • Diphosphomevalonate decarboxylase antibody
  • FP17780 antibody
  • MDDase antibody

  see all

Anti-MVD antibody 图像

• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MVD antibody (ab198823)

  Immunohistochemical staining of paraffin-embedded human brain tissue labeling MVD using ab198823 at a 1/30 dilution.