• 经测试应用IHC-Pmore details
• 种属反应性
  与反应: Human
• 免疫原

  Fusion protein corresponding to Human APOA4 (internal sequence). (BC113596).
  Database link: P06727

• 阳性对照
  • Human ovarian cancer and cervical cancer tissues.

性能

• 形式Liquid
• 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
• 存储溶液pH: 7.3
  Preservative: 0.05% Sodium azide
  Constituents: 50% Glycerol, 49% PBS
•  
• 纯度Immunogen affinity purified
• 克隆多克隆
• 同种型IgG
• 研究领域
  • Signal Transduction
   
  • Metabolism
   
  • Lipid metabolism

  • Cardiovascular
   
  • Atherosclerosis
   
  • Lipoprotein metabolism

  • Cardiovascular
   
  • Atherosclerosis
   
  • Lipid transport

  • Cardiovascular
   
  • Lipids / Lipoproteins
   
  • Lipoproteins/Apolipoproteins
  • Apolipoproteins

  • Cancer
   
  • Cancer Metabolism
   
  • Metabolic signaling pathway
  • Metabolism of lipids and lipoproteins

  • Cancer
   
  • Cancer Metabolism
   
  • Cellular metabolic process

  • Metabolism
   
  • Pathways and Processes
   
  • Metabolic signaling pathways
  • Lipid and lipoprotein metabolism
   
  • Lipid metabolism

  • Metabolism
   
  • Pathways and Processes
   
  • Metabolic signaling pathways
  • Lipid and lipoprotein metabolism
   
  • Lipoprotein metabolism

  • Metabolism
   
  • Types of disease
   
  • Heart disease

应用

靶标

• 相关性APOA4 (apolipoprotein A-IV) is a component of HDL and chylomicrons. Its primary site of synthesis is the intestine, in association with lymph chylomicron particles. Although its precise function is not known, APOA4 is a potent activator of lecithin-cholesterol acyltransferase (LCAT) in vitro. In rodents, Apo A-IV inhibits gastric emptying and serves as a satiety factor whose synthesis and secretion are increased by the ingestion of dietary fat. It also possesses anti-inflammatory and antiatherogenic properties
• 细胞定位Secreted

• Anti-APOA4 antibody 图像

  • 

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APOA4 antibody (ab197844)

    Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue labeling APOA4 with ab197844 at 1/30 dilution.

  • 

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APOA4 antibody (ab197844)