HLA-G monoclonal antibody, clone 4H84 (Biotin)
产品名称: HLA-G monoclonal antibody, clone 4H84 (Biotin)
英文名称: HLA-G monoclonal antibody, clone 4H84 (Biotin)
产品编号: MAB4487
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against HLA-G .
- Immunogen:
- Amino acid 61-83 of human HLA-G.
- Host:
- Mouse
- Theoretical MW (kDa):
- 39
- Reactivity:
- Human
- Specificity:
- This antibody recognizes HLA-G molecule (39 KDa). HLA-G belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on the surface of trophoblast cells.
- Form:
- Liquid
- Conjugation:
- Biotin
- Concentration:
- 1 mg/mL
- Isotype:
- IgG1
- Storage Buffer:
- In PBS, pH 7.4 (15 mM sodium azide)
- Storage Instruction:
- Store at 4°C. Do not freeze.
- Recommend Usage:
- Western Blot (2 ug/mL )
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Characterization of human leukocyte antigen-G (HLA-G) expression in endometrial adenocarcinoma.
Barrier BF, Kendall BS, Sharpe-Timms KL, Kost ER.Gynecol Oncol. 2006 Oct;103(1):25-30. Epub 2006 Mar 10.
- 2.
- A novel sandwich ELISA for alpha1 domain based detection of soluble HLA-G heavy chains.
Juch H, Blaschitz A, Daxbock C, Rueckert C, Kofler K, Dohr G.J Immunol Methods. 2005 Dec 20;307(1-2):96-106. Epub 2005 Nov 4.
- 3.
- The 4H84 monoclonal antibody detecting beta2m free nonclassical HLA-G molecules also binds to free heavy chains of classical HLA class I antigens present on activated lymphocytes.
Polakova K, Kuba D, Russ G.Hum Immunol. 2004 Feb;65(2):157-62.
- Application Image
- Western Blot
- Immunocytochemistry
- Immunoprecipitation
- ELISA
- Entrez GeneID:
- 3135
- Gene Name:
- HLA-G
- Gene Alias:
- MHC-G
- Gene Description:
- major histocompatibility complex, class I, G
- Gene Ontology:
- Hyperlink
- Gene Summary:
- HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq
- Other Designations:
- HLA class I molecule,HLA-G histocompatibility antigen, class I, G,MHC class I antigen,OTTHUMP00000039485,b2 microglobulin
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