HOXA5 polyclonal antibody
产品名称： HOXA5 polyclonal antibody
英文名称： HOXA5 polyclonal antibody
产品编号： PAB14649
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of HOXA5.
- Immunogen:
- A synthetic peptide corresponding to amino acids 142-161 of human HOXA5.
- Sequence:
- GVGTASGAEEDAPASSEQAS
- Host:
- Rabbit
- Reactivity:
- Bovine, Chicken, Chimpanzee, Dog, Human, Mouse
- Specificity:
- The amino acid sequence used as immunogen is 100% homologous in human, dog, chimp and bovine, and 90% homologous in mouse, and 85% in chicken.
- Form:
- Liquid
- Storage Buffer:
- In serum (50% glycerol, 0.025% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:100-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Identification of transcriptional targets of HOXA5.
Chen H, Rubin E, Zhang H, Chung S, Jie CC, Garrett E, Biswal S, Sukumar S.J Biol Chem. 2005 May 13;280(19):19373-80. Epub 2005 Mar 9.
- 2.
- HOXA5-twist interaction alters p53 homeostasis in breast cancer cells.
Stasinopoulos IA, Mironchik Y, Raman A, Wildes F, Winnard P Jr, Raman V.J Biol Chem. 2005 Jan 21;280(3):2294-9. Epub 2004 Nov 15.
- 3.
- HOXA5-induced apoptosis in breast cancer cells is mediated by caspases 2 and 8.
Chen H, Chung S, Sukumar S.Mol Cell Biol. 2004 Jan;24(2):924-35.
- Application Image
- ELISA
- Entrez GeneID:
- 3202
- Protein Accession#:
- NP_061975
- Gene Name:
- HOXA5
- Gene Alias:
- HOX1,HOX1.3,HOX1C,MGC9376
- Gene Description:
- homeobox A5
- Omim ID:
- 142952
- Gene Ontology:
- Hyperlink
- Gene Summary:
- In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis. [provided by RefSeq
- Other Designations:
- homeo box 1C,homeo box A5,homeobox protein HOXA5
- Related Disease