GSPT1抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
GSPT1抗体

GSPT1抗体

商家询价

产品名称： GSPT1抗体

英文名称： GSPT1Antibody

产品编号： XY10763-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 GSPT1抗体

Applications
In-house applications ELISA, WB, IHC     Application not tested? Please see our Guarantee.
Published applications IF, WB Publications 4 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Human, mouse
Images
Prev1NextView more validation data
  • 10763-1-AP;SGC-7901 cellSGC-7901 cells were subjected to SDS PAGE followed by western blot with 10763-1-AP(GSPT1 antibody) at dilution of 1:100
  • 10763-1-AP;Breast cancerImmunohistochemical of paraffin-embedded human breast cancer using 10763-1-AP(GSPT1 antibody) at dilution of 1:100 (under 10x lens)
Positive WB detected in SGC-7901 cells, HeLa cells
Positive IHC detected in Human breast cancer tissue
Recommended dilution WB : 1:200-1:1000
IHC : 1:20-1:200
 GSPT1抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen GSPT1 fusion protein ag1184 Full name G1 to S phase transition 1
Calculated molecular
weight		 68.4 kDa Observed molecular 
weight		 80 kDa; 84 kDa
GenBank accession 
number		 BC009503 Gene ID (NCBI) 2935
Gene symbol GSPT1 Synonyms 551G9.2, eRF3a, ETF3A, FLJ38048, FLJ39067, G1 to S phase transition 1, GSPT1, GST1
Background GSPT1抗体

The eukaryotic Release Factor 3 (eRF3) is a GTPase that associates with eRF1 in a complex that mediates translation termination. Eukaryotic release factor 3 (eRF3) has many functions in eukaryotic cells, such as controlling the regulation of the cell cycle at the G1 to S phase transition, and regulating protein synthesis as a GTP dependent stimulator of eRF1 in translation termination. It was also reported to play a key role as an initiator of the mRNA degradation machinery in the recycling of ribosomes in successive cycles of translation,and probably also in transcription regulation. GSPT1 is one subunit of eRF3[PMID:15917414,12923185]. It involves in translation termination in response to the termination codons UAA, UAG and UGA and stimulates the activity of ERF1. GSPT1抗体

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