Anti-14-3-3 delta + zeta (phospho T232)抗体-抗体-抗体-生物在线
深圳市宇德立生物科技有限公司
Anti-14-3-3 delta + zeta (phospho T232)抗体

Anti-14-3-3 delta + zeta (phospho T232)抗体

商家询价

产品名称： Anti-14-3-3 delta + zeta (phospho T232)抗体

英文名称： 14-3-3 protein zeta/delta antibody 1433Z_HUMAN antibody KCIP-1 antibody Protein kinase C inhibitor protein 1 antibody YWHAZ antibody

产品编号： ab195909

产品价格： null

产品产地： 英国

品牌商标： abcam

更新时间： null

使用范围：

深圳市宇德立生物科技有限公司
  • 联系人 :
  • 地址 : 深圳市宝安区西乡宝民二路贤基大厦4E
  • 邮编 :
  • 所在区域 : 广东
  • 电话 : 133****4454 点击查看
  • 传真 : 点击查看
  • 邮箱 : 1484332550@qq.com
进入展台

 

  • 特异性ab195909 detects endogenous levels of 14-3-3 delta + zeta only when phosphorylated at Threonine 232.
  • 经测试应用WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to Human 14-3-3 delta + zeta (phospho T232). (Derived from around the phosphorylation site of Threonine 232).
    Database link: P63104

  • 阳性对照
    • UV treated Jurkat whole cell lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • 存储溶液pH: 7.4
    Preservative: 0.02% Sodium azide
    Constituents: 50% Glycerol, 49% PBS, 0.87% Sodium chloride
  • 浓度100 µg 浓度为 1 mg/ml 
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG

应用

Our Abpromise guarantee covers the use of ab195909 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Abreviews 说明
WB   1/500 - 1/2000. Predicted molecular weight: 28 kDa.

靶标

  • 功能Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
  • 序列相似性Belongs to the 14-3-3 family.
  • 翻译后修饰The delta, brain-specific form differs from the zeta form in being phosphorylated (By similarity). Phosphorylation on Ser-184 by MAPK8; promotes dissociation of BAX and translocation of BAX to mitochondria. Phosphorylation on Thr-232; inhibits binding of RAF1. Phosphorylated on Ser-58 by PKA and protein kinase C delta type catalytic subunit in a sphingosine-dependent fashion. Phosphorylation on Ser-58 by PKA; disrupts homodimerization and heterodimerization with YHAE and TP53.
  • 细胞定位Cytoplasm. Melanosome. Located to stage I to stage IV melanosomes.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 14-3-3 protein zeta/delta antibody
    • 1433Z_HUMAN antibody
    • KCIP-1 antibody
    see all

Anti-14-3-3 delta + zeta (phospho T232) antibody 图像

  • Western blot - Anti-14-3-3 delta + zeta (phospho T232) antibody (ab195909)
    Western blot - Anti-14-3-3 delta + zeta (phospho T232) antibody (ab195909)
    All lanes : Anti-14-3-3 delta + zeta (phospho T232) antibody (ab195909) at 1/500 dilution

    Lane 1 : UV treated Jurkat whole cell lysate with antigen specific peptide
    Lane 2 : UV treated Jurkat whole cell lysate

    Lysates/proteins at 12.5 µg per lane.


    Predicted band size : 28 kDa