MAPK13 (Human) Recombinant Protein
产品名称: MAPK13 (Human) Recombinant Protein
英文名称: MAPK13 (Human) Recombinant Protein
产品编号: P5774
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human MAPK13 (NP_002745.1, 1 a.a. - 365 a.a.) full length recombinant protein with GST tag expressed in Escherichia coli.
- Theoretical MW (kDa):
- 69
- Form:
- Liquid
- Preparation Method:
- Escherichia coli expression system
- Purification:
- Glutathione sepharose chromatography
- Purity:
- 87 % by SDS-PAGE/CBB staining
- Activity:
- The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorecence-labeled substrate and Mg (or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip™3000.
Substrate : Modified Erktide. ATP: 100 µM.
- Storage Buffer:
- In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.05% Brij35, 1 mM DTT, 10% glycerol)
- Storage Instruction:
- Store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- SDS-PAGE Stained with Coomassie Blue
- Note:
- Result of activity analysis
-
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 5603
- Protein Accession#:
- NP_002745.1
- Gene Name:
- MAPK13
- Gene Alias:
- MGC99536,PRKM13,SAPK4,p38delta
- Gene Description:
- mitogen-activated protein kinase 13
- Omim ID:
- 602899
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and cellular stress. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase. [provided by RefSeq
- Other Designations:
- OTTHUMP00000016282,mitogen-activated protein kinase p38 delta,stress-activated protein kinase 4
- Gene Pathway
- Amyotrophic lateral sclerosis (ALS)
- Epithelial cell signaling in Helicobacter pylori infection
- Fc epsilon RI signaling pathway
- GnRH signaling pathway
- Leukocyte transendothelial migration
- MAPK signaling pathway
- Neurotrophin signaling pathway
- T cell receptor signaling pathway
- Toll-like receptor signaling pathway
- VEGF signaling pathway
- Related Disease