Anti-VPS37A Polyclonal Antibody
产品名称: Anti-VPS37A Polyclonal Antibody
英文名称: HCRP1;PQBP2;SPG53
产品编号: K005505P
产品价格: null
产品产地: 北京
品牌商标: Solarbio
更新时间: null
使用范围: WB IHC IF
北京索莱宝科技有限公司--实验室产品
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This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.