IDH2 polyclonal antibody
产品名称： IDH2 polyclonal antibody
英文名称： IDH2 polyclonal antibody
产品编号： PAB19266
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody rasied against synthetic peptide of IDH2.
- Immunogen:
- A synthetic peptide corresponding to 17 amino acids near N-terminus of human IDH2.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Purification:
- Peptide affinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1-2 ug/mL)
Immunohistochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 3418
- Protein Accession#:
- NP_002159
- Gene Name:
- IDH2
- Gene Alias:
- ICD-M,IDH,IDHM,IDP,IDPM,mNADP-IDH
- Gene Description:
- isocitrate dehydrogenase 2 (NADP+), mitochondrial
- Omim ID:
- 147650
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. [provided by RefSeq
- Other Designations:
- NADP+-specific ICDH,isocitrate dehydrogenase, mitochondrial,oxalosuccinate decarboxylase
- Gene Pathway
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
- Biosynthesis of alkaloids derived from shikimate pathway
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of phenylpropanoids
- Biosynthesis of plant hormones
- Biosynthesis of terpenoids and steroids
- Citrate cycle (TCA cycle)
- Glutathione metabolism
- Metabolic pathways
- Reductive carboxylate cycle (CO2 fixation)
- Related Disease
- Astrocytoma
- Blast Crisis
- Brain Neoplasms
- Chronic Disease
- Disease Progression
- Glioma
- Hematologic Diseases
- Leukemia, Myeloid, Acute
- Leukemia, Myelomonocytic, Chronic
- Lung Neoplasms
- Melanoma
- Myelodysplastic Syndromes
- Myeloproliferative Disorders
- Neoplasm Metastasis
- Oligodendroglioma
- Polycythemia Vera
- Primary Myelofibrosis
- Recurrence
- Skin Neoplasms