AANAT Rabbit pAb (APR21565N)
产品名称: AANAT Rabbit pAb (APR21565N)
英文名称: AANAT Rabbit pAb (APR21565N)
产品编号: APR21565N
产品价格: null
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围:
分子量:Calculated MW: 23kDa/28kDa 细胞定位:Cytoplasm 稀释方法:IF 1:50 - 1:200 总结:The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.