AANAT Rabbit pAb (APR21565N)-抗体-抗体-生物在线
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AANAT Rabbit pAb (APR21565N)

AANAT Rabbit pAb (APR21565N)

商家询价

产品名称: AANAT Rabbit pAb (APR21565N)

英文名称: AANAT Rabbit pAb (APR21565N)

产品编号: APR21565N

产品价格: null

产品产地: 美国

品牌商标: Leading Biology

更新时间: null

使用范围:

生物谷
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分子量:Calculated MW: 23kDa/28kDa

细胞定位:Cytoplasm

稀释方法:IF 1:50 - 1:200

总结:The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.