SNAP25 Rabbit pAb (APR17623N)
产品名称: SNAP25 Rabbit pAb (APR17623N)
英文名称: SNAP25 Rabbit pAb (APR17623N)
产品编号: APR17623N
产品价格: null
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围: WB (mouse brain, Mus musculus, Rattus norvegicus)
分子量:Calculated MW: 23kDa Observed MW: 25KDa 细胞定位:Cell junction, Cell membrane, Cytoplasm, Lipid-anchor, perinuclear region, synapse, synaptosome 稀释方法:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:20 - 1:100 总结:Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.