PROC (Human) Recombinant Protein (P01)
产品名称: PROC (Human) Recombinant Protein (P01)
英文名称: PROC (Human) Recombinant Protein (P01)
产品编号: H00005624-P01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
                            亚诺法生技股份有限公司(Abnova)
                            
                                
                            
                        
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 - 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
 - 邮编 : 11493
 - 所在区域 : 台湾
 - 电话 : +886-920**1152 点击查看
 - 传真 : 点击查看
 - 邮箱 : sales@abnova.com.tw
 
- Specification
 
- Product Description:
 - Human PROC full-length ORF ( NP_000303.1, 1 a.a. - 461 a.a.) recombinant protein with GST-tag at N-terminal.
 
- Sequence:
 - MWQLTSLLLFVATWGISGTPAPLDSVFSSSERAHQVLRIRKRANSFLEELRHSSLERECIEEICDFEEAKEIFQNVDDTLAFWSKHVDGDQCLVLPLEHPCASLCCGHGTCIDGIGSFSCDCRSGWEGRFCQREVSFLNCSLDNGGCTHYCLEEVGWRRCSCAPGYKLGDDLLQCHPAVKFPCGRPWKRMEKKRSHLKRDTEDQEDQVDPRLIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWIHGHIRDKEAPQKSWAP
 
- Theoretical MW (kDa):
 - 78.5
 
- Preparation Method:
 - in vitro wheat germ expression system
 
- Purification:
 - Glutathione Sepharose 4 Fast Flow
 
- Storage Buffer:
 - 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
 
- Storage Instruction:
 - Store at -80°C. Aliquot to avoid repeated freezing and thawing.
 
- Quality Control Testing:
 - 12.5% SDS-PAGE Stained with Coomassie Blue.

 
- Note:
 - Best use within three months from the date of receipt of this protein.
 
- MSDS:
 
Download
- Application Image
 
- Enzyme-linked Immunoabsorbent Assay
 
- Western Blot (Recombinant protein)
 
- Antibody Production
 
- Protein Array
 
- Entrez GeneID:
 - 5624
 
- GeneBank Accession#:
 - NM_000312.2
 
- Protein Accession#:
 - NP_000303.1
 
- Gene Name:
 - PROC
 
- Gene Alias:
 - PC,PROC1
 
- Gene Description:
 - protein C (inactivator of coagulation factors Va and VIIIa)
 
- Omim ID:
 - 176860
 
- Gene Ontology:
 - Hyperlink
 
- Gene Summary:
 - The PROC gene encodes protein C (EC 3.4.21.69), a vitamin K-dependent plasma glycoprotein that is a key component of the anticoagulant system. Protein C is cleaved to its activated form, 'activated protein C' (APC) on endothelial cells by the thrombin-thrombomodulin complex (MIM 176930; MIM 188040) and then acts as a serine protease to degrade the activated forms of coagulation factors V (F5; MIM 612309) and VIII (F8; see MIM 306700). Protein S (PROS1; MIM 176880), also a vitamin K-dependent plasma protein, functions as a cofactor to activated protein C.[supplied by OMIM
 
- Other Designations:
 - -
 
- Gene Pathway
 
- Related Disease
 
- Acute Disease
 - Cadaver
 - Cardiovascular Diseases
 - Chorioamnionitis
 - Coronary Artery Disease
 - Coronary Disease
 - Diabetes Mellitus, Type 2
 - Edema
 - Fetal Membranes, Premature Rupture
 - Genetic Predisposition to Disease
 - Inflammation
 - Kidney Failure, Chronic
 - Meningococcal Infections
 - Multiple Organ Failure
 - Obstetric Labor, Premature
 - Postoperative Complications
 - Pre-Eclampsia
 - Pregnancy Complications, Hematologic
 - Premature Birth
 
