TSHR monoclonal antibody, clone 3A6
产品名称： TSHR monoclonal antibody, clone 3A6
英文名称： TSHR monoclonal antibody, clone 3A6
产品编号： MAB6678
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against full length recombinant TSHR.
- Immunogen:
- Recombinant protein corresponding to full length human TSHR.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.1% proclin, 2% Block Ace)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Flow Cytometry (1-5 ug/mL)
The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- An improved Graves' disease model established by using in vivo electroporation exhibited long-term immunity to hyperthyroidism in BALB/c mice.
Kaneda T, Honda A, Hakozaki A, Fuse T, Muto A, Yoshida T.Endocrinology. 2007 May;148(5):2335-44. Epub 2007 Jan 25.
- 2.
- Human melanoma cells express functional receptors for thyroid-stimulating hormone.
Ellerhorst JA, Sendi-Naderi A, Johnson MK, Cooke CP, Dang SM, Diwan AH.Endocr Relat Cancer. 2006 Dec;13(4):1269-77.
- 3.
- TNFalpha mediates the skeletal effects of thyroid-stimulating hormone.
Hase H, Ando T, Eldeiry L, Brebene A, Peng Y, Liu L, Amano H, Davies TF, Sun L, Zaidi M, Abe E.Proc Natl Acad Sci U S A. 2006 Aug 22;103(34):12849-54. Epub 2006 Aug 14.
- Application Image
- Flow Cytometry
- Entrez GeneID:
- 7253
- Gene Name:
- TSHR
- Gene Alias:
- CHNG1,LGR3,MGC75129,hTSHR-I
- Gene Description:
- thyroid stimulating hormone receptor
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- seven transmembrane helix receptor,thyroid stimulating hormone receptor, isoform 2,thyrotropin receptor,thyrotropin receptor-I, hTSHR-I
- Related Disease
- Abortion, Habitual
- Congenital Hypothyroidism
- Connective Tissue Diseases
- Fetal Diseases
- Genetic Predisposition to Disease
- Goiter, Nodular
- Graves Disease
- Graves Ophthalmopathy
- Hashimoto Disease
- Hypertension
- Hypothyroidism
- Infection
- Infertility, Female
- Inflammation
- Insulin Resistance
- Mitral Valve Prolapse
- Musculoskeletal Diseases
- Pancreatic cancer
- Pancreatic Neoplasms